Pregnancy is a very particular moment in a woman’s life during which many functional and metabolic parameters are carefully monitored. Among others, blood glucose, gestational weight gain (GWG), and the risk of gestational diabetes mellitus [GDM and glycated hemoglobin (HbA1c)] are constantly checked to avoid the risk of developing maternal pregnancy-related complications.
These parameters have been taken into consideration by the Danish group of Andreas Munk Petersen in a recent study published in Maternal and Pediatric Nutrition. In this randomized double-blinded placebo-controlled study, 50 obese pregnant women were randomly assigned to the treatment groups to receive 4 capsules containing the De Simone Formulation (Vivomixx®, 450 billion live bacteria per day) or placebo, from gestational week 14–20 until delivery. All visits also included fecal sampling to evaluate the intestinal microbiota. Fecal analysis showed a significant increase in bacterial biodiversity in the group integrated with probiotic, thus demonstrating that Vivomixx® is able to modulate the intestinal microbiota in obese women during pregnancy.
In general, both groups showed neither adverse events nor side effects, confirming the safety of use of this product during pregnancy.
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Halkjaer S et al. Curr Dev Nutr 2020;4:nzaa095.
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