Slab51 Formulation
Science is key
SLAB51 is another specific 8-strain probiotic formulation developed by Prof. Claudio De Simone. While the SLAB51 formulation is similar to the DSF in terms of proportions and types of species, the fermentation process and the manufacturer differ. Thus, SLAB51 is a unique product.
The biological and immunological properties and the enzymatic activity of SLAB51 continue to be characterised through a growing number of publications. New mechanisms of action on the gut-brain axis and oxygen-sparing capacity have been elucidated in various clinical conditions such as Alzheimer’s disease, Parkinson’s disease, Lyme disease and COVID-19.
Veterinarians worldwide have also taken a significant interest in this probiotic formulation, and studies have been performed in different animal species.

Why probiotics?
The microorganisms living in your gut have numerous functions, the most important being the maintenance and integrity of the mucosal barrier, providing nutrients to the host, such as vitamins, and protecting against pathogens.
When beneficial bacteria are lost either through illness or treatments such as antibiotics, a state of dysbiosis is created. Probiotics can help replace the beneficial bacteria and restore the balance of your microflora.

SLAB51 is not just any probiotic.
Gut-Brain Axis
There exists a bidirectional communication network functionally linking the gut and the central nervous system (CNS), known as the gut-brain axis. The manipulation of intestinal microbiota with SLAB51 has been successfully investigated as a novel therapeutic strategy for CNS-associated disorders such as Alzheimer’s and Parkinson’s.
Lung-Brain Axis
More recently, this specific probiotic formulation has been shown to modulate the consumption of oxygen in the gut making more oxygen available for critical organs (i.e. brain, heart, liver). The “oxygen sparing effect” induced by SLAB51 has been scientifically proven in several studies, particularly in patients with COVID-19 infection.

Eight strains for teamwork
The strains contained in the SLAB51 blend have been selected for their specific individual characteristics and their capacity to work in synergy, achieving what individual strains or other strain combinations cannot.
The strains have been the object of numerous experimental and clinical studies confirming their safety and efficacy, particularly in the gut-brain and gut-lung axes.
A good probiotic is not identified by the number of strains or their concentrations; what actually matters is the clinical evidence that such a combination brings.
SLAB51 is available in various concentrations, from 10 billion to 800 billion active and vital bacteria per capsule or sachet. Consider that the number of microorganisms inhabiting the gastrointestinal tract is estimated to exceed 1014. In the colon alone, there can be up to 1012 cells per gram of intestinal contents. The proposed concentrations are necessary to colonise the gut and significantly modify the gut flora in specific patient groups.
DSF and cirrhosis
DSF modulates serum metabolites in patients with cirrhosis Thirty-two patients with cirrhosis and cognitive dysfunction [...]
Chronic sleep restriction
Counteract the deleterious effects of sleep deprivation with SLAB51 to reduce stress and relieve anxiety and fatigue [...]