Alzheimer’s disease is a neurovegetative disorder that sees genetic predisposition and infectious processes among the leading etiological causes. Among the latter are gingivitis and periodontitis. A review by the Taiwanese group of Chun-Pin Chiang1 wanted to deepen the issue and collected 26 articles on the main scientific search engines. This association was verified from the epidemiological point of view and post-mortem studies. The gene sequencing of the microbial of the oral cavity presented a constant predominance of Gram-negative bacteria as elements of inflammation of the oral cavity. This element, suggested the use of a specific strain of L. brevis for its anti-inflammatory capacities. A study on laboratory mice in which gingivitis was experimentally induced demonstrated a significant reduction of inflammation levels by the determination of proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6, and IL7A) by the action of the enzyme argininedeiminase present in the strain L. brevis itself. These findings have also been confirmed in human studies by Lee JK et al.3. Click here for more publications.