The human gut microbiota is a huge ecosystem that provides numerous functions for host development, immune system, and metabolism. Thus, imbalance in the gut microbiota can be linked to many diseases, including human metabolic diseases such as obesity, type 2 diabetes, irritable bowel syndrome, and cardiovascular disease. Few studies, however, have focused on the connection between aging and microbiota. Maoyang Lu and Zhao Wang have published an interesting review summarizing the role of the gut microbiota in aging processes with emphasis on therapeutic potential of microbiome-targeted interventions in anti-aging medicine. Over the past decades, the researchers highlighted the link between the alteration of gut microbial composition and aging, and aging-related disease. It has been found that gut microbiota changes during aging period and aging, in turn, affects the host health status by modulating the composition of the gut microbiota.1
Targeted products are now available to fight against aging-related diseases, and maintaining the intestinal well-being of elderly patient for prolonged periods represents a new therapeutic approach to improve health span and treat aging-related diseases.
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