The De Simone formulation has been tested in a considerable number of patients of all age groups The probiotic formulation of Pr. De Simone has been tested in over 5000 patients of all ages: 33 330 adult participants 1 682 children in pediatric studies 295 participants in geriatric studies The numerous studies and the large panel of participants have demonstrated the safe use of the De Simone formulation in patients of all ages. Pr De Simone, about Pr. Claudio De Simone2017-09-12T15:00:19+00:00De Simone Formulation, Probiotics| Share this article! FacebookTwitterLinkedInEmail Leave A Comment Cancel reply Comment Save my name, email, and website in this browser for the next time I comment.