De Simone Formulation
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The De Simone Formulation is the most concentrated medical food supplement that contains 8 different naturally strains of bacteria to help to maintain a healthy digestive system. It has been the subject of more than 60 clinical studies and over 200 original publications and approved by the major international gastroenterology associations. It was invented by medical doctor and professor of infectious disease and immunology – Claudio De Simone, MD, PhD.
What are probiotics?
Probiotics work in a variety of ways along your digestive tract – helping to balance the levels of microorganisms in the intestine and reduce the numbers of harmful bacteria that cause infections and other health problems.
When beneficial bacteria are lost due to illness or treatment such antibiotics, probiotics can help to replace them.
Probiotics can help balance your beneficial and harmful bacteria to keep your body working like it should.
Why is it important to maintain a healthy digestive system?
A healthy digestive system plays a huge part in a person’s well-being. A poorly functioning digestive tract can interfere with quality of life and be the source of many health problems.
It is important to maintain balance of your intestinal microflora. You need good intestinal balance to stay healthy. A healthy human digestive tract contains 500 different types of bacteria that play a vital role in reducing the growth of harmful bacteria.
The strains work in synergy
The strains contained in the blend have been selected for the specific characteristics and for their capacity to work in synergy and achieve what individual strains or other combinations of strains cannot achieve.
Recognised for its effectiveness and safety, Vivomixx has been tested successfully in more than 60 scientific medical studies and is distributed in many countries around the world.
450 billion bacteria in one sachet, equivalent to 360 yogurts
The De Simone Formulation contains 450 billion active and vital bacteria per sachet and 112 billion per capsule. These quantities are needed to properly colonize your gut to provide a healthy balance of good bacteria to support the intestinal system.
Why so many bacteria?
The De Simone Formulation contains 450 billion bacteria per sachet and 112 billion bacteria per capsule. These quantities are necessary to survive the journey to properly colonize your gut which contains up to 10-1000 billion bacteria/ml of feces material. In the colon there can be around 1500 ml of feces material.
60 clinical studies
Recognised for its effectiveness and safety, the De Simone Formulation has been tested successfully in more than 60 scientific medical studies and is distributed in many countries around the world.
170 articles and publications
The De Simone Formulation has been the subject of over 170 original publications and approved by the major international gastroenterology associations.
A promising new therapeutic approach for major depressive disorder targets the microbiota-gut-brain axis: novel evidence
A promising new therapeutic approach for major depressive disorder targets the microbiota-gut-brain axis: novel evidence Major depressive [...]
The potential contribution of the gut-muscle axis to the pathophysiology of sarcopenia and reduced physical capacity in COPD patients
The potential contribution of the gut-muscle axis to the pathophysiology of sarcopenia and reduced physical capacity in [...]
The promising role of DSF in fighting against autism
Autism spectrum disorders have an increasing prevalence characterized by enormous individual, family and social costs. There are [...]
Add-on probiotic therapy reduces seizures for drug-resistant epilepsy patients
Reduction in seizures following add-on probiotic therapy in patients with drug-resistant epilepsy. Drug-resistant epilepsy (DRE) occurs in [...]
Relevance of De Simone Formulation in hepatic encephalopathy
De Simone Formulation combined with rifaximin positively affect the neurometabolic profile in a rat model of type [...]
The De Simone formulation has been tested in a considerable number of patients of all age groups
The probiotic formulation of Pr. De Simone has been tested in over 5000 patients of all ages: 33 [...]
The Simone Formulation has been tested worldwide
The Simone Formulation has been tested worldwide Among the probiotics being studied, many are tested at a [...]
The De Simone formulation has been tested in many therapeutic areas
Since 2000, the Simone Formulation has been studied in a wide range of therapeutic fields: 39 studies were [...]
Formulation De Simone tested in rigorous clinical trials
Rigorous clinical trial standards to test the Simone Formulation In any clinical study, it is essential to avoid [...]
Frequently asked questions
What’s the recommended daily dose of the De Simone Formulation?
The recommended daily does is 1-2 sachets or 1-4 capsules. With the sachets, the contents can be dissolved in water yogurt and any other cold, non-carbonated drink.
When is the best time to take De Simone Formulation?
It is recommended to take Vivomixx before breakfast.
What is the optimal duration time for taking De Simone Formulation?
One may start to feel better after 3-4 days, but optimal colonisation is between 2-3 weeks.
Does De Simone Formulation contain any allergens?
Vivomixx does not contain gluten, lactose or soy. It does not contain preservatives or synthetic sweeteners.
Why should De Simone Formulation be kept refrigerated?
The De Simone Formulation is best kept cold, but can be kept out of the fridge at room temperature for up to one week without affecting the quality of the product. However, high temperatures (>25degrees C) should be avoided.
Where to purchase De Simone Formulation?