Childhood obesity is a growing problem worldwide. Recent research suggests that intestinal microbiota may play an important and potentially causal role in the development of obesity and could be a mechanism that explains the transgenerational transmission of obesity risk.
For this reason the Californian group of Maggie Stanislawski published on mBio, the official journal of the American Society for Microbiology, an interesting study in which the intestinal microbiota of early childhood was examined on days 4, 10, 30, 120, 365 and 730. Other factors taken into consideration were the link to the body mass index (BMI) at the age of 12 in a Norwegian prospective cohort (n = 165) to evaluate if and how these values associated with the BMI could relate to maternal overweight and excessive gestational weight.
Moreover, 16S rRNA gene sequencing was also performed on intestinal microbiota samples, which demonstrated that taxonomic phylogeny at 10 and 730 days is significantly associated with infantile BMI, to the point that the intestinal microbiota composition at 2 years of age was associated with over 50% of the change in infant BMI in this cohort.