Pr De Simone’s Blog, a Pioneer of the Gut Microbiota

Pr De Simone’s Blog, a Pioneer of the Gut Microbiota

When an efficacious food supplement* suffers from being just a “probiotic”

Probiotics are considered the «snake oil» of the millennium, and doctors are reluctant to explore their full potential. However, preliminary data suggest that oral bacteriotherapy might be helpful in the management of COVID-19 infected patients. The danger would be to either downplay the results on the general conviction that probiotics are not [...]

Not all probiotics work in the same way in IBD

When a high-concentration probiotic (De Simone Formulation) was first included in the Gastroenterology Guidelines for the dietary management for IBD (Inflammatory Bowel Diseases) patients, it caused quite a stir. Analyzing this strategy in depth has allowed researchers to identify essential differences between the components included in the wide range of food supplements.A [...]

Probiotics as a new strategy for patients with Klebsiella pneumoniae rectal colonization

Infections caused by KPC-2 producing Klebsiella pneumoniae (KPCKP), are an increasing threat for hospitalized patients, because of the ability of carbapenemasi enzyme (KPC) to confer antibiotic-resistance. The Spanish group led by Ana del Rio published an observational study (1) on the efficacy of a 10-day non-absorbable oral antibiotic (NAA) regimen vs. the [...]

Probiotics during pregnancy, intestinal health and well-being

Pregnancy is a very particular moment in a woman's life during which many functional and metabolic parameters are carefully monitored. Among others, blood glucose, gestational weight gain (GWG), and the risk of gestational diabetes mellitus [GDM and glycated hemoglobin (HbA1c)] are constantly checked to avoid the risk of developing maternal pregnancy-related [...]

High concentration probiotics in the arsenal to fight the Covid-19

A new prospective in Covid-19 management comes from the journal Frontiers in Medicine. Understanding the invasive process of SARS-COV-2 has been essential to show that viral infection deeply destabilizes the gut-lung axis, causing alteration in the respiratory functions. The fact that pneumonia and gastrointestinal symptoms are predominant clinical manifestations of COVID-19 [...]

Probiotics: a valuable add-on in SARS-CoV-2 infection

The Sars-Cov-2 coronavirus pandemic has spread widely around the world, causing often times serious clinical conditions such as severe pneumonia and cardiovascular syndrome, especially in patients with comorbidities, including diabetes and respiratory failure. Until a safe and effective vaccine is developed, the scientific community has highlighted some strategies to promptly intervene [...]

23 novel genera, emended description of the genus Lactobacillus

Since the description of the first Lactobacillus species, Lactobacillus delbrueckii, in 1901, over 260 species were assigned to this genus until March 2020. The availability of new DNA analysis tools over the years has shown that genus Lactobacillus was too diverse and did not conform to nomenclature conventions. According to several genetic approaches and phenotypic or ecologic [...]

Go to Top