Pr De Simone’s Blog, a Pioneer of the Gut Microbiota

Pr De Simone’s Blog, a Pioneer of the Gut Microbiota

Probiotics helping Parkinson’s disease patients

Parkinson is a neurodegenerative disorder characterized by motor and non-motor symptoms (such as depression, abnormalities in the gut function, pain, hyposmia), which may appear before the motor sign. Some treatments can help relieve Parkinson’s disease (PD)-associated symptoms, but there is no therapy to control the onset and progression of this disorder. [...]

A mouse model of lupus benefited from probiotic treatment during pregnancy and breastfeeding1

Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). This problem becomes particularly serious during pregnancy, with a worsening of the disease signs in post-delivery. The group coordinated by Xin M. Luo evaluated the structure of the intestinal microbiota in a mouse model [...]

Modulation of the intestinal microbiota to improve diabetic patients’ health

An interesting study has been presented at the annual EASD meeting (European Association for the Study of Diabetes) by a Czechoslovakian research group coordinated by Dr Kahleova and colleagues who studied how a low-fat vegan diet may induce changes in the composition of the intestinal microbiota in overweight and obese adults. The [...]

The microbiome of patients with Lupus influences their immunity

Patients with Systemic Lupus Erythematosus (SLE) have a particular intestinal microbiome characterized by a deep dysbiosis the intensity of which is proportional to the severity of the disease; one of the main consequences of this intestinal imbalance is the inability to protect the individual affected by SLE from infections triggered by commensal [...]

The De Simone Formulation approved by the scientific community

On November 18, 2018, the Maryland Court of Justice condemned the pharmaceutical companies, VSL. Inc., Leadiant and Alfasigma, distributors of the probiotic VSL#3, to pay $15 million for false advertising and having deceived patients and doctors. As a result of this court decision, scientific authorities now recognize the De Simone Formulation [...]

Screening for rheumatoid arthritis passes through the microbiome of our mouth

The key to arthritis management is early diagnosis and treatment to prevent further joint destruction and maximize functional ability. Osteoarthritis (OA) and rheumatoid arthritis (RA) are two common types of arthritis that the primary care provider must differentiate, in terms of diagnosis and treatment. Effective and non-invasive strategies for early detection [...]

Childhood obesity is written in the microbiota

Childhood obesity is a growing problem worldwide. Recent research suggests that intestinal microbiota may play an important and potentially causal role in the development of obesity and could be a mechanism that explains the transgenerational transmission of obesity risk. For this reason the Californian group of Maggie Stanislawski published on mBio, [...]