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A mouse model of lupus benefited from probiotic treatment during pregnancy and breastfeeding1

Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). This problem becomes particularly serious during pregnancy, with a worsening of the disease signs in post-delivery. The group coordinated by Xin M. Luo evaluated the structure of the intestinal microbiota in a mouse model of [...]

Modulation of the intestinal microbiota to improve diabetic patients’ health

An interesting study has been presented at the annual EASD meeting (European Association for the Study of Diabetes) by a Czechoslovakian research group coordinated by Dr Kahleova and colleagues who studied how a low-fat vegan diet may induce changes in the composition of the intestinal microbiota in overweight and obese adults. The [...]

The De Simone Formulation approved by the scientific community

On November 18, 2018, the Maryland Court of Justice condemned the pharmaceutical companies, VSL. Inc., Leadiant and Alfasigma, distributors of the probiotic VSL#3, to pay $15 million for false advertising and having deceived patients and doctors. As a result of this court decision, scientific authorities now recognize the De Simone Formulation [...]

Screening for rheumatoid arthritis passes through the microbiome of our mouth

The key to arthritis management is early diagnosis and treatment to prevent further joint destruction and maximize functional ability. Osteoarthritis (OA) and rheumatoid arthritis (RA) are two common types of arthritis that the primary care provider must differentiate, in terms of diagnosis and treatment. Effective and non-invasive strategies for early detection [...]

Childhood obesity is written in the microbiota

Childhood obesity is a growing problem worldwide. Recent research suggests that intestinal microbiota may play an important and potentially causal role in the development of obesity and could be a mechanism that explains the transgenerational transmission of obesity risk.For this reason the Californian group of Maggie Stanislawski published on mBio, the official [...]

And psychiatrists discovered the microbiota

The modalities with which the organism establishes its behaviour in the environment that surrounds it also passes through the intestine; this notion was hypothesized but still not confirmed based on the existing interconnections between the vagus nerve, the immune system, short-chain fatty acids and tryptophan. From an evolution standpoint, the babies [...]

Intervening on the intestinal bacterial flora to prevent hepatosteatosis

The well-known problem related to non-alcoholic fatty liver disease (NAFLD) is of significant incidence in obese individuals and often with an unstoppable evolution into cirrhosis and fibrosis, even in neoplasia. The study of this phenomenon over the years has highlighted a possible trigger of the pathology by environmental, genetic and metabolic factors, [...]