Parkinson is a neurodegenerative disorder characterized by motor and non-motor symptoms (such as depression, abnormalities in the gut function, pain, hyposmia), which may appear before the motor sign. Some treatments can help relieve Parkinson’s disease (PD)-associated symptoms, but there is no therapy to control the onset and progression of this disorder. [...]
We know that the bacterial colonization plays a key role for the intestinal health, but we now know that the intestinal bacterial flora may also be involved in other areas. Over the past ten years the research has increasingly focused on the role of the microbiota of the gut and colon [...]
Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). This problem becomes particularly serious during pregnancy, with a worsening of the disease signs in post-delivery. The group coordinated by Xin M. Luo evaluated the structure of the intestinal microbiota in a mouse model [...]
An interesting study has been presented at the annual EASD meeting (European Association for the Study of Diabetes) by a Czechoslovakian research group coordinated by Dr Kahleova and colleagues who studied how a low-fat vegan diet may induce changes in the composition of the intestinal microbiota in overweight and obese adults. The [...]
Patients with Systemic Lupus Erythematosus (SLE) have a particular intestinal microbiome characterized by a deep dysbiosis the intensity of which is proportional to the severity of the disease; one of the main consequences of this intestinal imbalance is the inability to protect the individual affected by SLE from infections triggered by commensal [...]
On November 18, 2018, the Maryland Court of Justice condemned the pharmaceutical companies, VSL. Inc., Leadiant and Alfasigma, distributors of the probiotic VSL#3, to pay $15 million for false advertising and having deceived patients and doctors. As a result of this court decision, scientific authorities now recognize the De Simone Formulation [...]
The key to arthritis management is early diagnosis and treatment to prevent further joint destruction and maximize functional ability. Osteoarthritis (OA) and rheumatoid arthritis (RA) are two common types of arthritis that the primary care provider must differentiate, in terms of diagnosis and treatment. Effective and non-invasive strategies for early detection [...]
Childhood obesity is a growing problem worldwide. Recent research suggests that intestinal microbiota may play an important and potentially causal role in the development of obesity and could be a mechanism that explains the transgenerational transmission of obesity risk. For this reason the Californian group of Maggie Stanislawski published on mBio, [...]
The modalities with which the organism establishes its behaviour in the environment that surrounds it also passes through the intestine; this notion was hypothesized but still not confirmed based on the existing interconnections between the vagus nerve, the immune system, short-chain fatty acids and tryptophan. From an evolution standpoint, the babies [...]