Recent publications confirm these observations.
A review paper of 2015, ‘Gut/Brain axis and the microbiota‘ published in The Journal of Clinical Investigation1, describes in the rat the bidirectional relationship between the central nervous system, the enteric nervous system, and the gastrointestinal tract. Future studies will naturally have to confirm these mechanisms for ASD in humans, but we may well expect confirmation of these experimental results.
Another review of studies on ASD Microbiome Disturbances and Autism Spectrum Disorders‘ published in the review Drug Metabolism and Disposition2 gives an update on various possibilities on how to take care of dysbiosis and gastrointestinal disorders, I quote:
« Autism spectrum disorders (ASDs) are considered a heterogenous set of neurobehavioral diseases, with the rates of diagnosis dramatically increasing in the past few decades. As genetics alone does not explain the underlying cause in many cases, attention has turned to environmental factors as potential etiological agents. Gastrointestinal disorders are a common comorbidity in ASD patients. It was thus hypothesized that a gut-brain link may account for some autistic cases. With the characterization of the human microbiome, this concept has been expanded to include the microbiota-gut-brain axis. There are mounting reports in animal models and human epidemiologic studies linking disruptive alterations in the gut microbiota or dysbiosis and ASD symptomology. »
1 Gut/Brain axis and the microbiota
Mayer et al 2015 The Journal of Clinical Investigation 125.3:926-938
2 Microbiome Disturbances and Autism Spectrum Disorders
Cheryl S. Rosenfeld et al 2015 Drug Metab Dispos 43:1557–1571, October 2015