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So far Pr. Claudio De Simone has created 276 blog entries.

The De Simone Formulation approved by the scientific community

On November 18, 2018, the Maryland Court of Justice condemned the pharmaceutical companies, VSL. Inc., Leadiant and Alfasigma, distributors of the probiotic VSL#3, to pay $15 million for false advertising and having deceived patients and doctors. As a result of this court decision, scientific authorities now recognize the De Simone Formulation [...]

Screening for rheumatoid arthritis passes through the microbiome of our mouth

The key to arthritis management is early diagnosis and treatment to prevent further joint destruction and maximize functional ability. Osteoarthritis (OA) and rheumatoid arthritis (RA) are two common types of arthritis that the primary care provider must differentiate, in terms of diagnosis and treatment. Effective and non-invasive strategies for early detection [...]

Childhood obesity is written in the microbiota

Childhood obesity is a growing problem worldwide. Recent research suggests that intestinal microbiota may play an important and potentially causal role in the development of obesity and could be a mechanism that explains the transgenerational transmission of obesity risk.For this reason the Californian group of Maggie Stanislawski published on mBio, the official [...]

And psychiatrists discovered the microbiota

The modalities with which the organism establishes its behaviour in the environment that surrounds it also passes through the intestine; this notion was hypothesized but still not confirmed based on the existing interconnections between the vagus nerve, the immune system, short-chain fatty acids and tryptophan. From an evolution standpoint, the babies [...]

Intervening on the intestinal bacterial flora to prevent hepatosteatosis

The well-known problem related to non-alcoholic fatty liver disease (NAFLD) is of significant incidence in obese individuals and often with an unstoppable evolution into cirrhosis and fibrosis, even in neoplasia. The study of this phenomenon over the years has highlighted a possible trigger of the pathology by environmental, genetic and metabolic factors, [...]

Does the treatment of obesity and diabetes go through the intestine? 1

In this paper from Harvard, the group led by Ronald Kahn wondered why obesity and diabetes were associated with increased rates of anxiety and depression, suspecting intestinal function involvement.To understand the relationship between the gut microbiome and brain insulin resistance in these disorders, Kahn's study evaluated behaviors and insulin action in brain [...]