Pr De Simone’s Blog, a Pioneer of the Gut Microbiota

Pr De Simone’s Blog, a Pioneer of the Gut Microbiota

About Pr. Claudio De Simone

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So far Pr. Claudio De Simone has created 407 blog entries.

DSF and cirrhosis

DSF modulates serum metabolites in patients with cirrhosis Thirty-two patients with cirrhosis and cognitive dysfunction or a history of falls were enrolled in a recent study by Soriano, Laghi, and colleagues. The scope of the trial was to explore new approaches to improve cirrhotic patients' outcomes and health-related quality [...]

Chronic sleep restriction

Counteract the deleterious effects of sleep deprivation with SLAB51 to reduce stress and relieve anxiety and fatigue Sleep is a vital behavior that significantly impacts physical and mental well-being. Chronic sleep restriction (CRS), defined as inadequate sleep, is linked to an increased risk of chronic diseases and brain deficits, [...]

Further Evidence for the Role of Probiotics in Depression

Further Evidence for the Role of Probiotics in Depression Recent scientific research has been uncovering the intestinal microbiome's impact on the nervous system's development and functioning. The gut microbiome and specific neurobiological pathways are known as the "microbiome-gut-brain axis.” There are two main paths through which information can flow [...]

SLAB51 to spare oxygen during infections from respiratory syncytial virus, COVID-19 and influenza

SLAB51 to spare oxygen during infections from respiratory syncytial virus, COVID-19 and influenza By Professor Claudio De Simone  From Medical Xpress Newspaper headlines from the U.S. to the U.K. and most places in between highlight the surge in sick patients suffering from respiratory viruses. The so-called "tripledemic" of lung [...]

2023-01-17T09:06:10+01:00Covid, Slab51|

Study confirms Probiotic SLAB51 benefits COVID-19 hypoxic patients

Study confirms Probiotic SLAB51 benefits COVID-19 hypoxic patients Successful management of acute respiratory distress syndrome (ARDS) resulting from COVID-19 infection requires balancing adequate oxygenation and avoiding ventilator-induced lung injury (VILI). Recently reported data in Biomedicines (1) revealed that individuals with severe COVID-19 infections who required non-invasive oxygen therapy needed significantly less oxygen [...]

2022-12-08T16:55:07+01:00Covid, Slab51|

A promising new therapeutic approach for major depressive disorder targets the microbiota-gut-brain axis: novel evidence

A promising new therapeutic approach for major depressive disorder targets the microbiota-gut-brain axis: novel evidence Major depressive disorder is one of the most common mental disorders and in some individuals it can result in severe impairments that interfere with or limit the ability to carry out major life activities. The concept [...]

The potential contribution of the gut-muscle axis to the pathophysiology of sarcopenia and reduced physical capacity in COPD patients

The potential contribution of the gut-muscle axis to the pathophysiology of sarcopenia and reduced physical capacity in COPD patients Chronic obstructive pulmonary disease (COPD) is an inflammatory condition of the respiratory system which can also affect multiple organs. Most patients with COPD develop muscle weakness and atrophy, which contribute to functional [...]

A Brief History of the De Simone Formulation

On March 25, 2022, I was invited to a Round Table organized by the distributors of my Formulation in Serbia. This video from the conference is divided into two sections. The first section (from the beginning to minute 7) outlines the history of my probiotic formulation. Bacteria as (or even better [...]