Pr. Claudio De Simone

Le blog d'un pionnier du microbiote intestinal:/Pr. Claudio De Simone

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So far Pr. Claudio De Simone has created 258 blog entries.

Autoimmune responses against intestinal bacteria are linked with type 1 diabetes

Microbiome sequence analyses have suggested that changes in gut bacterial composition are associated with autoimmune disease in humans and animal models. The mechanisms through which the gut microbiota influences autoimmune responses are still barely known. In a recent study, Jayne S. Danska and colleagues evaluated systemic antibody responses against cultured human [...]

High concentration probiotics for healthier aging

The human gut microbiota is a huge ecosystem that provides numerous functions for host development, immune system, and metabolism. Thus, imbalance in the gut microbiota can be linked to many diseases, including human metabolic diseases such as obesity, type 2 diabetes, irritable bowel syndrome, and cardiovascular disease. Few studies, however, have focused [...]

The De Simone Formulation approved by the scientific community

On November 18, 2018, the Maryland Court of Justice condemned the pharmaceutical companies, VSL. Inc., Leadiant and Alfasigma, distributors of the probiotic VSL#3, to pay $15 million for false advertising and having deceived patients and doctors. As a result of this court decision, scientific authorities now recognize the De Simone Formulation [...]

Screening for rheumatoid arthritis passes through the microbiome of our mouth

The key to arthritis management is early diagnosis and treatment to prevent further joint destruction and maximize functional ability. Osteoarthritis (OA) and rheumatoid arthritis (RA) are two common types of arthritis that the primary care provider must differentiate, in terms of diagnosis and treatment. Effective and non-invasive strategies for early detection [...]

Childhood obesity is written in the microbiota

Childhood obesity is a growing problem worldwide. Recent research suggests that intestinal microbiota may play an important and potentially causal role in the development of obesity and could be a mechanism that explains the transgenerational transmission of obesity risk.For this reason the Californian group of Maggie Stanislawski published on mBio, the official [...]