The blog of a pioneer of the intestinal microbiota:Home/Pr. Claudio De Simone

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So far Pr. Claudio De Simone has created 295 blog entries.

Probiotics: a valuable add-on in SARS-CoV-2 infection

The Sars-Cov-2 coronavirus pandemic has spread widely around the world, causing often times serious clinical conditions such as severe pneumonia and cardiovascular syndrome, especially in patients with comorbidities, including diabetes and respiratory failure. Until a safe and effective vaccine is developed, the scientific community has highlighted some strategies to promptly intervene [...]

23 novel genera, emended description of the genus Lactobacillus

Since the description of the first Lactobacillus species, Lactobacillus delbrueckii, in 1901, over 260 species were assigned to this genus until March 2020. The availability of new DNA analysis tools over the years has shown that genus Lactobacillus was too diverse and did not conform to nomenclature conventions. According to several genetic approaches and phenotypic or ecologic [...]

A mouse model of lupus benefited from probiotic treatment during pregnancy and breastfeeding1

Dysbiosis of gut microbiota exists in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (lupus). This problem becomes particularly serious during pregnancy, with a worsening of the disease signs in post-delivery. The group coordinated by Xin M. Luo evaluated the structure of the intestinal microbiota in a mouse model of [...]

Modulation of the intestinal microbiota to improve diabetic patients’ health

An interesting study has been presented at the annual EASD meeting (European Association for the Study of Diabetes) by a Czechoslovakian research group coordinated by Dr Kahleova and colleagues who studied how a low-fat vegan diet may induce changes in the composition of the intestinal microbiota in overweight and obese adults. The [...]

Antimicrobial resistance: act now

Since their discovery, antibiotics have served as the cornerstone of modern medicine. However, the persistent overuse and misuse of antibiotics in human and animal health have encouraged the emergence and spread of antibiotic resistance, which occurs when microbes, such as bacteria, become resistant to the drugs used to treat them. On 18th [...]